MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.
Increasing evidence shows that dysregulation of microRNAs (miRNAs) is involved in malignant transformation.We investigated the clinical significance of miR-650 and its involvement in chemoresistance to docetaxel.Our results showed that the relative expression level of miR-650 was significantly higher in LAD tissues than in corresponding nontumor ti