MICRORNA-650 WAS A PROGNOSTIC FACTOR IN HUMAN LUNG ADENOCARCINOMA AND CONFERS THE DOCETAXEL CHEMORESISTANCE OF LUNG ADENOCARCINOMA CELLS VIA REGULATING BCL-2/BAX EXPRESSION.

MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.

Increasing evidence shows that dysregulation of microRNAs (miRNAs) is involved in malignant transformation.We investigated the clinical significance of miR-650 and its involvement in chemoresistance to docetaxel.Our results showed that the relative expression level of miR-650 was significantly higher in LAD tissues than in corresponding nontumor ti

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Radiotherapy for subependymal giant cell astrocytoma: time to challenge a historical ban? A case report and review of the literature

Abstract Background Subependymal giant cell astrocytoma is a benign brain tumor that occurs in patients with tuberous sclerosis complex.Surgical removal is the traditional treatment, and expert opinion is strongly against the use of radiotherapy.Recently, success has been reported with the mTor inhibitor everolimus in reducing tumor volume, but reg

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